Dr Sharma is a graduate of prestigious Lady Hardinge Medical College, New Delhi, India and a post graduate in ENT from Safdarjung Hospital, New Delhi India. She is also a Diplomat of National Board (DNB) in ENT. To start her journey of becoming an accomplished head and neck cancer surgeon she chose Tata Memorial Cancer Hospital, Mumbai, India as the first step, which is the best institute and mecca for any aspiring cancer surgeon. Further she went on to complete M.Ch in Head and Neck Cancer Surgery from the same institute. Dr Shilpi Sharma has been associated with some of the best hospitals in India like National Cancer Institute, Nagpur and Tata Memorial Cancer Hospital, Mumbai, India.

She has been a regular invitee as speaker and panelist in numerous national and international conferences. Dr Sharma is extensively involved in training and teaching aspiring head and neck cancer surgeons. In order to constantly upgrade her skill she keeps attending various confecrences, training programmes and seminars in India as well as abroad.